Mulgrew Miller made a huge impact on jazz history. He will be forever remembered. Here is a nice line over a 2-5-1.
He uses the same pattern over both the two chord and the five chord. He goes from the b9 to the #9 to the 3rd then back down to the natural 9, b13 and 3rd again. In the first measure he does start with the root though.
In the second measure I also like how he finishes with the #9 and b9 again and resolves down to the fifth of the Fmaj7.
Practice using similar patterns over each chord in a 2-5-1 to create a motif.
Enjoy!